Water Soluble CBD Oil

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Water soluble CBD powders and water soluble CBD oils are a great way to get a dose of CBD on the go. Here are our top picks for the best water soluble CBD brands. A recent study by researchers affiliated with Colorado State University has found that water-soluble cannabidiol products provide the best absorption of CBD, shedding new light on best practices for consumers seeking the benefits of the popular cannabinoid. Quality water-soluble CBD mixes easily into water and other liquids because it has been emulsified. Learn more about water-soluble CBD and how it works!

The Best Water Soluble CBD Products

There’s no shortage of CBD products on the market today, especially when it comes to CBD oils, gummies, and capsules. Among the different flavor options, CBD strengths, and types of hemp extracts (like full spectrum CBD oil vs CBD isolate), there is another potential option: water soluble CBD. What is water soluble CBD and what are the best brands to try? We cover it all in this article.

What is Water Soluble CBD?

Cannabidiol (CBD for short) is a well-known cannabinoid found within cannabis plants that is widely used as a wellness supplement in oil form.

Water soluble CBD oils and powders are up-and-coming products that exist primarily to simplify the process of adding CBD to beverages. Traditional CBD oil tinctures don’t blend as well into liquid drinks because the oil is less dense than water and separates easily. However, water soluble CBD may also provide other advantages through its potential enhancement of bioavailability.

Water soluble CBD products are made with nano emulsified CBD, or tiny particle sized CBD molecules that make it easier for the bloodstream to absorb the compound. These nano CBD particles are more compatible with water, despite the hydrophobic nature of macro CBD molecules that usually have to be infused with oil based products. This is a common process that has been used in pharmaceutical medicine for years, and the technology may prove to be beneficial in the CBD industry as well. CBD-infused water is an easy way to get a microdose of CBD that may promote general health and wellness from the inside out.

Our Favorite Water Soluble CBD Products

Each product featured here has been independently selected by the writer. You can learn more about our review methodology here. If you make a purchase using the links included, we may earn commission.

  • Best Overall – Prima Brain Fuel CBD Powder
  • Strongest – CBDistillery CBDelicious CBD Isolate Powder
  • Best for Energy – Joy Organics CBD Energy Drink Mix
  • Best Flavor – Liweli Super Lemon CBD Drink Mix

How We Picked the Best Water Soluble CBD Products

To create our list of recommended water soluble CBD brands, we compared each one on a number of key factors. Here are the things we looked for in each product:

  • Strength — How much CBD does the mix include, and what type of CBD is it?
  • Source — Where does the company get their hemp and how do they extract their CBD?
  • Flavor — Does it come in any flavors and do they flavor them naturally?
  • Transparency — Can you access third-party lab test results and information about each batch of CBD?
  • Value — Is the product priced fairly for the amount of CBD included?
  • Packaging — How is the product packaged and is it environmentally-friendly or sustainable?

These categories helped us choose our favorite water soluble CBD products. Find out more about each of them below.

The Top Water Soluble CBD Products of 2022

Best Overall: Prima Brain Fuel CBD Powder

  • CBD – Broad Spectrum
  • Strength – 15 mg CBD per serving
  • Other Ingredients – Ashwagandha, Rhodiola, Lion’s Mane, Ginkgo
  • Great For – Focus

Why buy: We love this Brain Fuel CBD powder from Prima because it contains broad spectrum whole plant CBD extract plus nootropic and adaptogenic herbs like ashwagandha root, rhodiola root, lion’s mane, and ginkgo leaf extract. Mix this into a beverage to help promote focus and ease mental fatigue. We also love Prima’s commitment to sustainability, as all of their products are certified Plastic Negative to remove more plastic from the environment than they use in packaging.

Strongest: CBDistillery CBDelicious CBD Isolate Powder

  • CBD – CBD Isolate
  • Strength – 970 mg+ CBD per 1 gram
  • Other Ingredients – None
  • Great For – Cooking & Mixing

Why buy: This CBDelicious CBD Isolate powder is a great way to get CBD without using an oil tincture. We love this water soluble CBD product from CBDistillery because it offers a pure and potent amount of CBD isolate that makes it easy to add CBD as an ingredient in food or beverages.

Best for Energy: Joy Organics CBD Energy Drink Mix

  • CBD – Broad Spectrum
  • Strength – 12.5 mg CBD per serving
  • Other Ingredients – Aloe Vera Leaf Powder, Asian Ginseng Root Powder, Maca Root Powder, Caffeine, Stevia
  • Great For – Energy

Why buy: This CBD Energy Drink mix powder is a great way to start your day or to get through the afternoon lull. We love that it contains 12.5 mg of broad spectrum CBD and 75 mg of caffeine for an energizing boost, making it a natural alternative to super-sugary energy drinks.

Best Flavor: Liweli Super Lemon CBD Drink Mix

  • CBD – Broad Spectrum
  • Strength – 25 mg CBD per serving
  • Other Ingredients – Natural Lemon Zest Flavor, Acacia Fiber
  • Great For – Recovery

Liweli water soluble CBD packets make getting a regular dose of CBD simple and convenient. You can keep these lemon-flavored pouches in your purse or backpack and add them to your drink of choice.

Why buy: We like the Liweli Super Lemon CBD Drink Mix because they dissolve well, which is key for a product like this, and taste great. Liweli is a best bet for anyone on-the-go. Use these water soluble CBD packets to help with sore muscles or aches from exercise.

The Research on Water Soluble CBD

Besides the convenience of mixing CBD in with your favorite beverage or food, water soluble CBD products are also growing in popularity because they may be much easier for the body to absorb than regular CBD hemp oil. This is due to the increased absorption rates of the nano CBD particles, or its bioavailability. One study published in the journal Phytotherapy Research found that water soluble CBD powder had a bioavailability 4.5 times higher than lipid-soluble CBD powder. The more CBD that your body is able to absorb per serving, the better effect it can have helping to support your health and wellness.

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Is Water Soluble CBD Better Than CBD Oil?

While they each have their own benefits, and limitations, water soluble CBD may help to support your mind and body in a number of different ways. One isn’t necessarily better than the other. The best option for you comes down to a matter of personal preference. Some people will find that they prefer a water soluble CBD powder that they can mix in with a beverage if they do not enjoy the taste of a CBD oil tincture. A water soluble product is also more convenient for use on-the-go or while traveling. CBD oils, however, typically offer higher strengths of CBD, and come in full spectrum formulas that contain all of the other beneficial cannabinoids and plant compounds found in hemp extract.

Benefits of Water Soluble CBD

Water soluble CBD offers many of the same potential benefits as CBD oil, including support in managing stress, anxiety, inflammation, and certain forms of pain. Water soluble CBD may also prove to be more cost effective if its bioavailability is truly greater than traditional CBD tinctures, although more research is needed to validate this assumption. One primary benefit of water soluble CBD is that it can offer a pre-measured amount of CBD with each individual serving or packet. This makes it easy to know exactly how much CBD you are getting each time.

How to Choose the Best Water Soluble CBD Brand for You

To help you compare your options and choose the right one for you, here are some important things to keep in mind when shopping for water soluble CBD.

What to Look For

When considering water soluble CBD, be sure to look for:

Type of CBD: Make sure you know whether the product contains full spectrum, broad spectrum, or CBD isolate hemp extract.

Concentration: Look to see how much CBD is contained in each serving of the product, or in total if it is not packaged in individual doses.

Lab Testing: Always look for products that include independent third-party lab testing for their CBD products. This helps to ensure its safety and concentration.

How to Read Labels

Here are some key things to look for on the label of any water soluble CBD product.

  • Strength – The label should clearly indicate how many milligrams of CBD there are per serving, and how many servings are contained in the box or package.
  • Test Results – Many brands include a QR code on the label or box for you to access the lab test results to confirm the purity of the CBD.
  • Added Ingredients – Look for the ingredients list to check what other botanicals or extracts are included in the product, especially if you have any allergies.
  • Instructions – Be sure to read any directions or instructions included on the label to make sure you are getting the most out of your water soluble CBD.

How to Use

Water soluble CBD powders and products are relatively simple to use. They can easily be added into any food or beverage for a discreet and easy way to ingest CBD. Most brands recommend stirring the powder into warm or cold water until it is completely mixed in before drinking. Some advise that it works best to add the powder to your cup or glass before adding the water. You can also stir water soluble CBD into smoothies, juices, or teas to get even more out of your favorite drink. Take CBD-infused water in the morning to start the day, or, if it is a formula designed to help you sleep, before bed in the evening.

Safety & Side Effects

According to the Mayo Clinic, CBD products are generally safe and well-tolerated by most adults. Like all CBD supplements, however, water soluble CBD may cause certain mild side effects. These can include:

  • Dry mouth
  • Diarrhea
  • Reduced appetite
  • Drowsiness
  • Fatigue

CBD also carries a risk of interacting with certain prescription medications. Make sure you consult with your doctor if you take a prescription before adding CBD to your wellness routine.

Is Water Soluble CBD Right for You?

Water soluble CBD powders are a great option for people who prefer to get their daily dose of CBD without taking an oil tincture. They are also easy to take with you to the gym or while traveling. Use our guide to find the right option for you to enjoy CBD-infused water to help support your wellness naturally.

Melena Gurganus is the Reviews Editor at EcoWatch. She is passionate health and wellness and her writing aims to help others find products they can trust. Her work has been featured in publications such as Health, Shape, Huffington Post, Cannabis Business Times, and Bustle.

New Study Suggests Water-Soluble Cannabidiol Products Provide Best CBD Absorption

A recent study by researchers affiliated with Colorado State University has found that water-soluble cannabidiol products provide the best absorption of CBD, shedding new light on best practices for consumers seeking the benefits of the popular cannabinoid. The study, which was published last month in the peer-reviewed journal Nutrients, also explored the effects that cannabidiol has on digestion and determined that CBD products are best consumed with food for maximum absorption, among other findings.

The research, which was conducted in conjunction with Colorado State University’s Department of Health and Exercise Science, compared the absorption of five different CBD formulations in 14 male test subjects. Products studied included CBD diluted in medium-chain triglycerides (MCT) coconut oil, CBD isolate, and three different water-soluble CBD ingredients. The goal of the study was to document how each of these formulations of CBD entered and left the bloodstream and at what rate. Additionally, the study profiled how the formulations interacted with liver functionality and if there was evidence that food intake and metabolism were affected by the products.

New research shows that taking water-soluble cannabidiol products with food provided the best . [+] absorption of CBD.

Water-Soluble CBD Had Best Absorption

The study found that water-soluble CBD preparations displayed superior pharmacokinetics compared to oil-based CBD. One of the water-soluble CBD preparations used in the study was created using proprietary technology from NextEvo Naturals, which has proven to significantly improve bioavailability. John McDonagh, CEO of the company, said that the research sheds new light on how consumers can get the most out of the CBD products they take.

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“While the potential health benefits of CBD have been widely publicized, this new data suggests consumers should be very aware of the pharmacokinetic differences between commercial CBD formulations, for example, how the CBD you are taking gets absorbed into the body,” McDonagh said in a statement from NextEvo. “We set out to prove that our product formulations may actually be able to offer the many benefits of CBD because they enter the bloodstream quickly and efficiently.”

The results of the study, which NextEvo notes have not been evaluated by the U.S. Food and Drug Administration, show a more than 500% variance in maximum blood concentration achieved between water-soluble CBD ingredients compared to oil-based formulations and unformulated CBD isolate. The variance represents a significant difference in the body’s ability to absorb and process CBD, which is necessary to reap the potential health and wellness benefits of the cannabinoid.

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Taking CBD With Food Increases Absorption

The results also showed that consuming water-soluble CBD with food greatly increases the body’s absorption of CBD and modifies early insulin and triglyceride responses. Six hours after consumption, CBD concentration in the bloodstream was three times higher when consumed with food compared to taking the product after fasting. David Chernoff, MD, chief medical officer at NextEvo, says that the research revealed CBD’s potential positive effect on insulin and triglyceride levels.

“Our study results show that within 30 minutes after eating a meal, CBD appeared to lower insulin and triglyceride levels. The exact mechanism of how CBD impacts insulin levels and triglyceride levels is unclear as the CBD levels 30 min post-meal are very low,” Chernoff writes in an email. “What one can infer from these findings is that CBD may have a favorable effect on how fats and sugars are metabolized after a meal so CBD might be beneficial for supporting healthy glucose and lipid metabolism.”

Researchers have long debated if eating a meal or fasting could affect CBD’s absorption into the bloodstream. Some have found that it helps to eat when taking oil-soluble CBD, but the new research suggests that taking water-soluble CBD products with food will provide the most benefit.

“We’ve found that the best way for consumers to take CBD is in a product containing a water-soluble formulation with a meal. This allows the body the opportunity for maximum absorption into the bloodstream,” writes Chernoff. “The more CBD the body absorbs, the more likely the consumer is to experience CBD’s potential benefits.”

CBD is available in a variety of product formulations.

“This is one of the first studies to examine the potential benefits CBD has on digestion and whether it should be administered with food,” NextEvo wrote in a statement about the research. “The study provides significant evidence that consuming CBD with food alters the dynamics of CBD metabolism and increases systemic availability, favorably modifying early insulin and triglyceride responses.”

The research also revealed new evidence on the safety of CBD. The study showed that CBD taken at average doses, in this case, 30mg per dose, does not evoke physiologically relevant changes in markers of liver function, suggesting that CBD probably does not represent a risk to the liver.

Potential limitations of the study identified by the researchers include a small sample size and the fact that all test subjects were male, although the authors wrote that they “have no reason to suspect the potential for sex differences.”

A report on the study, “Cannabidiol and Cannabidiol Metabolites: Pharmacokinetics, Interaction with Food, and Influence on Liver Function,” was published online by the journal Nutrients in May.

Understanding Water-Soluble CBD

There are numerous CBD-infused products on the market today, from tinctures to tablets, from beverages to edibles. Many of these items contain water-soluble CBD — but what does that mean for a product producer trying to decide how to integrate CBD into a sparkling water or a gummy, or to the consumer trying to decide what product to buy? How is water-soluble CBD different from oil? Is it easier to produce a product with water-soluble? Does the body absorb water-soluble cannabinoids differently than oils?

Consumers are curious about CBD – how it’s extracted from the plant, how it’s integrated into products, and what its potential benefits are. Here we will explain what water-soluble CBD is — how it is made, its benefits, the formats that it comes in, and what to look for when evaluating water-soluble products.

What is Water-Soluble CBD?

Simply put, water-soluble CBD is CBD that can be dispersed in water and other liquids. When extracted from the hemp or cannabis plant, CBD and other cannabinoids are oils, which can be challenging to work with in terms of the sensory profile, dosage control, reliable and repeatable onset and duration, manufacturing, and labelling.

Making CBD water-soluble by emulsifying the cannabinoid gives infused food and beverage producers the ability to create products that taste great, are accurately dosed, and that offer predictable, repeatable experiences for the consumer.

Water-Soluble CBD Benefits

To understand the benefits water-soluble CBD in the form of an emulsion delivers, it’s important to explain how the body processes oil extracts first. When an oil-based cannabinoid is ingested, its bioavailability is limited because the oil is hydrophobic, meaning that it is incompatible with or insoluble in water. This means that the human body, which is over 60% water, has difficulty absorbing and processing the oil.

Another factor is that first pass metabolism also inhibits bioavailability. When CBD oils are ingested orally, the GI tract absorbs them and delivers them to the liver via the portal vein. The liver metabolizes them, and from there, a limited amount moves to the circulatory system. The end result is that cannabinoids in oil form are not readily absorbed by the body, and the onset can take a few hours.

In contrast, the body is more able to process and absorb water-soluble CBD because the oil, which is embedded in the emulsion, is recognized by the body as hydrophilic, or water-friendly. Emulsion technology breaks the oil down into small particle sizes for even dispersion and stability, which allows for greater absorption in the intestinal tract. This means that consumers experience the effects of water-soluble CBD between 10 and 20 minutes after ingestion.

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How is Water-Soluble CBD Made?

Method #1: Physical Dispersion

There are a few ways CBD can be made water-soluble; the first is through physical dispersion – think, shaking your bottle of oil and vinegar to create a salad dressing! While this method is easy to prepare and execute with low capital cost, the resulting material is prone to settling, clumping, and layering; it also does not protect the CBD oil from oxidation. In terms of the sensory profile, the weedy/grassy flavors and aroma persist.

Method #2: Ultrasonic Dispersions

The second is through ultrasonic dispersions, where very small droplets are produced through cavitation generated by propagating a sonic wave through the product. This capital-intensive method requires the use of surfactants and brings with it some challenges when it comes to scale up and labeling of organic or all natural products.

Method #3: Co-solvents

The third method involves the use of co-solvents, where the CBD oil is solvated in water-miscible solvents. While this method does provide decent solubility and uniformity, there are potential label claim concerns because of the solvents, the flavor and aroma persist, and the formula is prone to scalping – where the CBD adheres to the lining of the can.

Method #4: Water-Soluble Emulsions

The fourth method is through creating an emulsion . The act of emulsification reduces a cannabinoid’s oils, or any oil for that matter, to very small, protected droplets. An emulsifier is brought into the equation so that the oil droplets will remain dispersed as individual droplets as opposed to grouping back together and separating from the water again. With this process, the new liquid is an oil and water combination that plays nicely together. In fact, when done correctly, the oil droplets prefer to be uniformly and equally distributed throughout the surrounding liquid. Once an emulsion has been made, analytic equipment is used to test particle size, stability, and homogeneity – all important elements of a high–quality emulsion.

If the cannabinoids were left in their-oil based state and a beverage product developer tried to add that oil to water, the oil would rise to the top. Not only would the first sip be a less than appealing one, but the cannabinoids would not be evenly dispersed throughout the beverage, which is an important factor to consider for a safe, consistent experience.

An easy way to think about how emulsions behave is to imagine dropping food coloring into a glass of water. The color will eventually disperse evenly and completely transform the color of the water. (See video below)

A successful emulsion will have consistent particle size, 12+ months’ stability and homogeneity, balanced density, and accurate dosing throughout the formula. A broken emulsion will show signs of creaming (oil rising to the top), ringing (oil settling around the edges), sedimentation (settling at the bottom), and flocculation (clumping).

Forms of Water-Soluble CBD

Water-soluble CBD typically comes in two forms: liquid and powder.

  • Liquid is ideal for ready-to-drink beverages and personal care items.
  • Standard Powder is ideal for baked goods and other food items.

Agglomerated Powder, which SōRSE has offered since 2019, allows for rapid hydration when dropped into liquid. That makes it the best solution for ready-to-make beverages like stick-packs.

How to Use Water-Soluble CBD

There are a variety of water-soluble CBD products on the market, and many consumers wonder which is the best format for taking CBD. Some formulations such as drops or tinctures can be taken under the tongue (sublingually). This rate of absorption is relatively fast and efficient, because the tissue in the mouth and under the tongue is highly vascular – meaning the tissue contains blood cells which will absorb the CBD.

Many consumers ingest water-soluble CBD orally, via products like beverages, edibles, capsules, tablets, or powders. When choosing between an edible like a brownie and a beverage, it’s important to know that the onset times can be very different given the amount of fat in the edible. As mentioned earlier, it takes longer for the body to process fat, which means that it may take longer for the consumer to feel the CBD’s effects after eating the brownie than they would if they had consumed a beverage.

What to Look for in Water-Soluble CBD

A high-quality water-soluble CBD will have the following qualities that will benefit the product producer and the consumer.

    • Safe ingredients: The emulsion is made with safe ingredients commonly found in the food and beverage industry.
    • Homogeneity: The emulsion evenly disperses when added to the product formula.
    • Stability: The emulsion remains shelf stable for 12 months.
    • Accurate dosing: Homogeneity and stability allows for near-perfect dosing and accurate label claims
    • Improved sensory: The emulsion can make an ingredient like CBD that has a bitter or disagreeable sensory effect more palatable. It can also allow a product producer to control the flavor profile.
    • Quality assurance: The producer of the water-soluble CBD should have established quality and safety standards, internal and third party testing, and documentation to verify quality and safety.

If you are a product developer, selecting the water-soluble CBD to infuse your product with will be one of the most important decisions you make during formulation because it impacts the entire product development process as well as the consumer’s experience with your product. Taste, stability, product consistency, dosing, and scalability are all incredibly important attributes in any emulsion. Throughout this evaluation process, it’s important to remember that you are not only looking at the quality of the emulsion; you are also choosing a strategic partner that can support you from concept to commercialization.

The team at SōRSE not only offers liquid and powder emulsions designed for easy integration into food, beverages, and personal care products, but also guidance through every stage of product development. If you are looking for a high-quality CBD emulsion powered by a team of experienced food scientists and product developers to get your product to market fast, now is the time to come to the SōRSE.

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