In addition, more trials are needed to investigate its use for numerous other conditions, such as muscle-spasticity in multiple sclerosis, Alzheimer’s disease, substance-abuse treatment, and diabetes protection.
Conclusion: Topical CBD may be beneficial at relieving arthritis but no high-quality human studies prove this.
More recent research points to THC being more effective at reducing nausea and vomiting than CBD.
9. Nausea and vomiting
Animal studies have shown some effect of CBD at relieving depression, possibly related to its strong anti-stress effect after either acute or repeated administration. 16
Conclusion: CBD is beneficial for treating certain types of epilepsy.
Animal studies have shown that CBD has a positive effect on serotonin levels in the brain, and serotonin. Low levels of serotonin are thought to play a key role in mood as well as pain. 11
A case series of 47 people with multiple sclerosis reported improvements in pain, walking, and muscle spasms with a combination of CBD and THC. 15
This broad-spectrum oil contains other supplements touted for natural immune support, like elderberry, echinacea, vitamin C, and ginger root. With 750 milligrams of broad-spectrum CBD per bottle, it’s also non-GMO, made in the U.S., third-party lab tested, and certified by the U.S. Hemp Authority.
We compared some of the most popular THC-free CBD oils to find the best ones available to buy online, based on potency, transparency around third-party lab testing, brand reputation, customer reviews, price, and other ingredients used.
The best THC-free CBD oils
This product is available in strengths of 20, 40, or 80 milligrams per serving, and the line also includes lotions, salves, gummies, and CBD for pets.
As mentioned before, THC-free CBD oil allows you to enjoy the benefits of cannabis without any THC. All CBD products in the U.S. are legally required to contain less than 0.3 percent THC, but some people prefer to leave it out altogether.
One of the main reasons people choose THC-free CBD oil is that it will not show up on a drug test, as some full-spectrum CBD products can. This allows you to take CBD during work hours to reduce anxiety and improve sleep without having to worry about it impacting your job duties and responsibilities. CBD oil is also legal in all U.S. states and easily accessible in most, though certain states have varying degrees of restriction. And since these CBD products contain no THC, they don't require certifications or recommendations from a physician to consume or purchase them.
“If you take pure CBD, it’s pretty safe,” said Marcel Bonn-Miller, an adjunct assistant professor at the University of Pennsylvania’s Perelman School of Medicine. Side effects in the Epidiolex trial included diarrhea, sleepiness, fatigue, weakness, rash, decreased appetite and elevated liver enzymes. Also, the safe amount to consume in a day, or at all during pregnancy, is still not known.
Last year, the F.D.A. approved Epidiolex, a purified CBD extract, to treat rare seizure disorders in patients 2 years or older after three randomized, double-blind and placebo-controlled clinical trials with 516 patients that showed the drug, taken along with other medications, helped to reduce seizures. These types of studies are the gold standard in medicine, in which participants are divided by chance, and neither the subject nor the investigator knows which group is taking the placebo or the medication.
Just as hemp seedlings are sprouting up across the United States, so is the marketing. From oils and nasal sprays to lollipops and suppositories, it seems no place is too sacred for CBD. “It’s the monster that has taken over the room,” Dr. Brad Ingram, an associate professor of pediatrics at the University of Mississippi Medical Center, said about all the wild uses for CBD now. He is leading a clinical trial into administering CBD to children and teenagers with drug-resistant epilepsy.
Does CBD help sleep and depression?
By Dawn MacKeen
take your money?
“Our top therapies attempt to break the association between reminders of the trauma and the fear response,” said Mallory Loflin, an assistant adjunct professor at the University of California, San Diego and the study’s principal investigator. “We think that CBD, at least in animal models, can help that process happen a lot faster.” While large clinical trials are underway, psychologists say there isn’t compelling evidence yet as to whether this is a viable treatment.
Many soldiers return home haunted by war and PTSD and often avoid certain activities, places or people associated with their traumatic events. The Department of Veterans Affairs is funding its first study on CBD, pairing it with psychotherapy.