If you have concerns that your pet is suffering adverse effects from ingesting cannabis or any substance containing cannabis, consult your veterinarian, local animal emergency hospital or an animal poison control center immediately.
10. Is it legal, in interstate commerce, to sell a food (including any animal food or feed) to which THC or CBD has been added?
These GRAS conclusions do not affect the FDA’s position on the addition of CBD and THC to food.
Children and Pregnant/Lactating Women
A. The FDA is aware that there are potential adverse health effects with use of cannabis products containing THC in pregnant or lactating women. Published scientific literature reports potential adverse effects of cannabis use in pregnant women, including fetal growth restriction, low birth weight, preterm birth, small-for-gestational age, neonatal intensive care unit (NICU) admission, and stillbirth. [1, 2, 3] Based on published animal research, there are also concerns that use of cannabis during pregnancy may negatively impact fetal brain development. [4, 5, 6 ] The American College of Obstetricians and Gynecologists (ACOG) recommends that women who are pregnant or contemplating pregnancy should be encouraged to discontinue cannabis use. In addition, ACOG notes that there are insufficient data to evaluate the effects of cannabis use on breastfed infants; therefore, cannabis use is discouraged when breastfeeding.  Pregnant and lactating women should talk with a health care provider about the potential adverse health effects of cannabis use.
FDA continues to be concerned at the proliferation of products asserting to contain CBD that are marketed for therapeutic or medical uses although they have not been approved by FDA. Often such products are sold online and are therefore available throughout the country. Selling unapproved products with unsubstantiated therapeutic claims is not only a violation of the law, but also can put patients at risk, as these products have not been proven to be safe or effective. This deceptive marketing of unproven treatments also raises significant public health concerns, because patients and other consumers may be influenced not to use approved therapies to treat serious and even fatal diseases.
FDA has approved Epidiolex, which contains a purified form of the drug substance CBD for the treatment of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome in patients 1 years of age and older. It has also approved Epidiolex for the treatment of seizures associated with tuberous sclerosis complex in patients 1 year of age or older. That means FDA has concluded that this particular drug product is safe and effective for its intended use.
4. Aside from Epidiolex, are there other CBD drug products that are FDA-approved? What about the products I’ve seen in stores or online?
Hemp oil for anxiety is a particularly useful application as it fills a gap that THC is typically unable to meet. Many users report anxiety as a side effect of marijuana use, but CBD is able to effectively treat and reduce it.
Believe it or not, we have barely scratched the surface when it comes to potential hemp uses. There are thousands of applications for this incredibly versatile plant.
Hemp’s most prominent purpose right now seems to be for personal wellness. For good reason. Many people consider it’s medicinal uses and benefits to the cure to everything, and it might be.
This is why cannabidiol or CBD becomes so important. It has similar benefits to THC, meaning the body will relax and release tension, but there will be no psychoactive effect making it safe for children to use.
Depending on your state, you may need to receive a license for producing or manufacturing hemp products. You will also need to register each year with the Department of Agriculture.
Many use hemp flower to feel a relaxing, meditative state while their 420 friends smoke marijuana and get blazed out of their minds.
Hemp does best in a warm, but the sustainable environment. Soil that will drain well is also optimal, making some parts of the country a natural fit for this super plant.
Center for Food Safety and Applied Nutrition. FDA Responds to Three GRAS Notices for Hemp Seed-Derived Ingredients for Use in Human Food. Available at: https://www.fda.gov/food/cfsan-constituent-updates/fda-responds-three-gras-notices-hemp-seed-derived-ingredients-use-human-food. Accessed December 20, 2019.
Lopez HL, Cesareo KR, Raub B, et al. Effects of hemp extract on markers of wellness, stress resilience, recovery and clinical biomarkers of safety in overweight, but otherwise healthy subjects. J Diet Suppl. 2020;17(5):561-86. View abstracts.
Uses & Effectiveness ?
Mikulcová V, Kaspárková V, Humpolícek P, Bunková L. Formulation, characterization and properties of hemp seed oil and its emulsions. Molecules. 2017;22(5). pii: E700. View abstract.
Rezapour-Firouzi S, Arefhosseini SR, Ebrahimi-Mamaghani M, et al. Activity of liver enzymes in multiple sclerosis patients with Hot-nature diet and co-supplemented hemp seed, evening primrose oils intervention. Complement Ther Med. 2014;22(6):986-93. View abstract.
Statement from FDA Commissioner Scot Gottlieb, M.D., on signing of the Agriculture Improvement Act and the agency’s regulation of products containing cannabis and cannabis-derived compounds. U.S. Food and Drug Administration Web site. Available at: https://www.fda.gov/news-events/press-announcements/statement-fda-commissioner-scott-gottlieb-md-signing-agriculture-improvement-act-and-agencys. (Accessed May 7, 2019).