Remember, because CBD oils are largely unregulated, there is no guarantee that a product is either safe or effective.
Here is just some of what the current evidence says.
Clinical research has shown that CBD oil can trigger side effects. Severity and type can vary from one person to the next.
What to Look For
Here are a few tips to help you find the best CBD oil:
To determine an exact dose of CBD, remember that each drop of oil equals 0.05 mL of fluid. This means that a 30-mL bottle of CBD oil will have roughly 600 drops. If the concentration of the tincture is 1,500 mg/mL, one drop would contain 2.5 mg of CBD (1,500 mg ÷ 600 drops = 2.5 mg).
CBD oil comes as full-spectrum oils or in forms that contain CBD isolates. Unlike isolates, which contain CBD only, full-spectrum oils contain a variety of compounds found naturally in the cannabis plant, including proteins, flavonoids, terpenes, and chlorophyll. Alternative practitioners believe these compounds offer more substantial health benefits, although there is no clear evidence of this.
CBD oil contains CBD mixed with an inert carrier oil, such as coconut oil or hemp seed oil. The bottled oil, called a tincture, is sold in various concentrations. There are also CBD capsules, CBD gummies, and under-the-tongue CBD sprays.
Whole hemp seeds contain 20% soluble and 80% insoluble fiber. The fiber in hemp seeds may help digestion. It may also help lower bad cholesterol and improve heart health. The insoluble fiber in hemp seeds has also been linked to a lower risk of diabetes.
Regulations on hemp grown in U.S., Europe, and Canada are stricter than in other countries, such as China.
Hemp Oil Vs. CBD Oil
Hemp oil is also called hempseed oil. It is made by cold-pressing hemp seeds. Hempseed oil is different from CBD oil. CBD oil is extracted from the cannabis plant and then combined with a base oil. Examples of base oils include coconut or olive oil.
Hemp seeds are, as the name implies, the seeds of the hemp plant. Hemp hearts are seeds that have had the shell removed.
Eating hemp seeds is not considered as unsafe as is eating hemp leaves or other parts of the plant. But because of the high fat content, the seeds can cause mild diarrhea.
Del Bo’ C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. Food Res Int. 2019;119:469-476. View abstract.
Gavel NT, Edel AL, Bassett CM, et al. The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits. Acta Physiol Hung. 2011;98(3):273-83. View abstract.
Insufficient Evidence for
Rezapour-Firouzi S, Arefhosseini SR, Ebrahimi-Mamaghani M, et al. Activity of liver enzymes in multiple sclerosis patients with Hot-nature diet and co-supplemented hemp seed, evening primrose oils intervention. Complement Ther Med. 2014;22(6):986-93. View abstract.
Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. View abstract.
Moccia S, Siano F, Russo GL, et al. Antiproliferative and antioxidant effect of polar hemp extracts (Cannabis sativa L., Fedora cv.) in human colorectal cell lines. Int J Food Sci Nutr. 2019:1-14. View abstract.