Two recent high quality randomised and placebo controlled trials showed that cannabidiol is an effective treatment for Lennox-Gastaut syndrome and Dravet syndrome, severe forms of epilepsy. The mechanism of action is unknown, but it may be due to a combination of effects, such as inhibiting the activity of neurons and dampening inflammation in the brain.
In the USA for example, cannabidiol is classed as a schedule 1 controlled substance, and can only be sold in states where cannabis use is legal.
That’s a complicated question. In the UK cannabidiol is legal. Cannabis plant extracts (known as hemp or CBD oils) are available in high-street stores but the THC content must be below 0.2 per cent. “THC is not psychoactive at this level,” says David Nutt, a neuropsychopharmacologist at Imperial College London. But cannabidiol is illegal in many other countries.
The situation is less clear when it comes to the use of commercial cannabis oils to control seizures, where the evidence is mainly anecdotal, and the oils can contain differing concentrations of cannabidiol and THC.
Not yet. In April the US Food and Drug Administration recommended the approval of a drug called Epidiolex for Lennox-Gastaut syndrome and Dravet syndrome. Its active ingredient is cannabidiol, and final approval is due at the end of this month.
The nature of THC is biphasic, which means that low to moderate doses can ease anxiety and relieve stress, whereas higher doses can elevate anxious feelings and trigger paranoid thinking patterns.
Understanding the difference between CBD and THC should clear up any confusion you may have about the possibility of getting high from CBD oil.
What is CBD?
What do we mean by negligible amounts of THC?
However, you can still experience a wide range of health benefits associated with using cannabinoids. People use CBD oil to feel focused, relaxed, invigorated, pain-free, and better rested on top of many other goals.
There’s a fine line between psychoactive and intoxicating.
Ultimately, vaping THC oil can lead to a substance use disorder. In fact, according to the National Institute on Drug Abuse, between 9% and 30% of people who use marijuana develop some sort of substance use disorder. And, people who begin using marijuana before they turn 18 are four to seven times more likely than adults to develop a marijuana use disorder.
Vaping THC oil involves heating the oil and inhaling it through a vaporizing device like a vape pen or an e-cigarette. Some people believe that vaping THC oil is safer than smoking because it doesn’t involve inhaling smoke. But the issue is that vaping hasn’t been around long enough and there isn’t enough research to really determine whether or not it’s safer.
Recreational use of marijuana, which contains THC, is now legal in 11 states. But the Food and Drug Administration has not approved the use of THC and it remains classified illegal under U.S. law. Still, people are experimenting with the drug more and more frequently by either smoking it, eating it, or vaping it.
What You Need to Know
Marijuana use, and more specifically vaping THC oil, is on the rise according to the National Institute on Drug Abuse. In fact, in 2018, more than 11.8 million young adults had used marijuana in the last year. Meanwhile, the number of teens in 8th and 10th grades who say they use it daily also has increased. Additionally, nearly 4% of 12th graders say they vape THC daily.
Even though several states allow medical marijuana that contains THC, it is still illegal under federal law. Some states have even made recreational marijuana legal, but it’s also illegal under U.S. law.
In fact, a study that appeared in the Journal of the American Medical Association found that first-time and infrequent users of marijuana were more likely to experience adverse reactions from vaping THC oil. They indicated that these negative impacts were largely due to the enhanced delivery of the oil through vaping. The participants in the study also had more pronounced effects from the drug and experienced significant impacts to their motor skills and cognitive abilities.
THC also affects your body differently than CBD does. Even though it works like CBD to impact neurotransmitters in your brain, THC is the main psychoactive compound found in marijuana and is the substance that will make you feel “high.”