CHICAGO—Despite the complicated politics surrounding medical marijuana, cannabis has a wide variety of medical benefits and potential benefits, but the risks need to be understood, said Daniel Clauw, MD, director of the Chronic Pain and Fatigue Research Center at the University of Michigan, in a session at the ACR’s 2016 State-of-the-Art Clinical Symposium.
Of the 80 cannabinoids found in cannabis plants, the two most important are tetrahydrocannabinol (THC) and cannabidiol (CBD). THC has mostly CB1-type effects on the central nervous system. Cannabidiol has no psychoactive effects, and it’s not clear where it binds in the body, but it appears to protect against the psychoactive effects of THC.
You Might Also Like
It’s important to understand the body’s endocannabinoid system to understand how the drugs work, he said. The system is a set of receptors and their natural ligands, plus enzymes that regulate them. There are two main receptor types: CB1, which mainly affects the central nervous system and the brain, and CB2, which is found in the periphery and affects the immune system and nerve cells.
“We don’t know what the optimal ratio of THC to CBD is,” Dr. Clauw said. “We know it’s likely good to have some CBD.”
‘Even if we end up replacing one problem for another, [marijuana] is a safer addiction, if you will, than the opioid addiction.’ —Daniel Clauw, MD
Why shouldn't you be allowed to discuss it? You are entitled to your opinion just as I am entitled to point out that there is currently no evidence to support the use of Cannabis oil in the treatment of Vasculitis.
For me, I feel I have gone through enough of the toxic meds yet I am no better in reality, I just seem to be adding more medications to an already huge list, these are not cures but are treating symptoms. I believe that I owe it to myself to try another way. I had a close friend who had the most virulent form of MS and although he died, he had several years of huge relief from his pain and suffering but that was through smoking it. I don't want to smoke it so am going for the oil. I have been very lucky in finding "help" on Facebook. I will be taking it mixed in coconut oil and rectally at first then orally as well. I want to start gently as I don't want to feel high as such. I will update as and when this happens and will maybe write a blog.
Tetrahydrocannibinol is one of the many active chemicals in cannibus. The beauty of this plant is it does SO many things some of which include anti- inflammatory without immune suppression. It makes the cells behave properly so they don't attack themselves. It also builds bone for those with osteoporosis like myself, coats nerves and helps in production of myelin around the nerves, gets rid of inflammation in the joints, is calming for those with anxiety. It helps with seizures of all types as well. Too many benefits to list. There are a lot of studies in countries that use plants on a regular basis for medicine. I know Isreal has some great published studies and there are a few being done in the US in states that allow it. Another great resource is looking up certified cannibus suppliers. Many have great information online or links to studies. There are NO documented deaths from using this plant and if used properly no side effects except drowsiness (which many medicines cause as well) in people that use high doses for certain things. Generally speaking those people are so few it's almost not worth mentioning. The only obvious reason for the governmental push back is this plant does so much it will put a huge financial drain on the pharmaceutical companies who pad the pockets of all our government held offices.
It was me that quoted that statistic, not Jools. I didn't mean to unduly alarm but point out that Vasculitis was a " serious " illness that needed prompt, effective treatment.
here is a website that I came across. Might be interesting. All I know is that cannabis is a miracle drug and lots of studies are being done.
John, as for the pharma companies, I have learned not to trust them. It's my personal opinion that they are not looking to cure but rather to treat symptoms and one only has to look at the many thousands of remedies to treat the common cold. I AM cynical because I have learned to be so. The use of many of the biologic drugs has no long term data and it's flying in the dark in reality. I hate the fact that I have to stay out of the sun now. That really sits badly with me. I am just a guy who is trying his own experiments is all. I have been on steroids close to 9 years and been on many differing immunosuppressive drugs. I am in a great deal of pain and if I can only achieve some relief from pain then I will be happy with that.
I just think that it would be remiss of me not to try an alternative way and I hope to be able to report that I have some positive things to say.
If you have arthritis or any other rheumatic condition, you have chronic inflammation. Ongoing inflammation causes pain and stiffness and damages the affected tissues. But you can fight inflammation with safe, natural supplements.
CBD is a cannabinoid — a compound that comes from the cannabis plant. However, unlike THC (tetrahydrocannabinol), which is another compound found in the cannabis plant, CBD does NOT contain any hallucinogenic effects or the “high” that some claim to get from THC.
Instead, CBD offers soothing, pain-reducing effects without the negative side effects associated with THC. This is why CBD is making an undeniable impact on the medical community. Just within the past couple years, the medical community has been forced to take a very serious look at cannabis, something that may have seemed ridiculous just a few years ago.
What is CBD?
Dr. Khaleghi is a board certified rheumatologist and takes pride in seeing his patients who suffer from inflammation leave with hope, mobility — and no more pain. Schedule a visit to Pacific Rheumatology Medical Center today by giving us a call or using the online scheduling tool.
CBD oil is applied topically to the skin like a lotion. One jar of CBD oil lasts for a long time, as a little bit goes a long way. And because it isn’t a narcotic like other painkillers, and it’s not ingested like ibuprofen, CBD oil cannot be abused and is not addictive. And no, you won’t smell like marijuana after rubbing it into your skin. CBD oil is simply a more natural and healthy way to attack pain from the outside rather than the inside.
You Might Also Enjoy.
You may be like countless other people who immediately reach for the ibuprofen when it comes to treating pain associated with inflammation. But there’s an increasingly popular alternative way to deal with these symptoms. CBD (cannabidiol) oil is quickly becoming the go-to solution for those suffering from chronic pain due to inflammation.