“There is a great deal of interest in the possible therapeutic effects of CBD, but there is very little evidence of efficacy,” said Dr. J Hampton Atkinson, co-director of the Center for Medical Cannabis Research (CMCR) at the University of California, San Diego. CBD may have health benefits, but the lack of research in this area means there just aren’t enough data points to support most of the anecdotal claims. Along that same line, the lack of research also means the potential health risks of consuming CBD are unclear.
Within the CMCR, there is also “much interest in the possible anti-inflammatory effects of CBD, for use in arthritis of various types, including knees and hands,” Atkinson said. Recent in vitro research with human cell lines afflicted with rheumatoid arthritis has suggested that CBD treatment may help reduce inflammation.
Research on CBD
Every variety of the cannabis family produces cannabinoids, including hemp. While CBD and THC are the most well-known cannabinoids, there are many different types, and only recently have significant resources been poured into their study. Our brains have specific receptors designed to accept cannabinoids, known as CB1 and CB2. These receptors are responsible for the assimilation of cannabinoid molecules into your system, resulting in the psychoactive and immune responses correlated with cannabis consumption.
CBD, short for cannabidiol, is a trending ingredient the natural products industry and is the focus of a new area of cannabis research. CBD is one of many cannabinoids, or molecules produced uniquely by the cannabis family. Unlike tetrahydrocannabinol (THC, the primary psychoactive element in marijuana), CBD is non-psychoactive, meaning it doesn’t have a strong effect on cognitive brain activity and doesn’t cause the “high” associated with marijuana.
In the last few years, there have been many advances in cannabis processing and consumption methods. Concentrated products such as oil and rosin (a sap-like product extracted via heat and pressure) have allowed for cleaner ingestion methods, such as vaporization, to become more widespread. These new technologies have brought more consistent, identifiable dosages to patients and enthusiasts alike, while potentially enabling safer methods of consumption. Finally, more accurate and detailed studies of cannabis effects and usage are underway, as prohibition continues to be challenged.
The discovery of the endocannabinoid system has significantly advanced our understanding of health and disease. It has major implications for nearly every area of medical science and helps to explain how and why CBD and THC are such versatile compounds – and why cannabis is such a widely consumed plant, despite its illegal status.
Figuring out how to optimize one’s therapeutic use of cannabis is the driving force behind the great laboratory experiment in democracy known as medical marijuana that’s been unfolding state-by-state and country-by-country in recent years.
How Does CBD Work?
In response to the FDA ’s historic decision, the Drug Enforcement Administration ( DEA ) announced in September 2018 that it had removed Epidiolex from Schedule I classification, a category reserved for dangerous drugs with no medical value. Henceforth, Epidiolex would be considered a Schedule V drug, the least dangerous designation under the Controlled Substances Act. The DEA later “descheduled” Epidiolex and removed it from the federal government’s list of controlled substances.
There’s a lot of excitement about the healing potential of CBD – with good reason.
CBD is closely related to another important medicinally active phytocannabinoid: tetrahydrocannabinol ( THC ), the compound that causes the high that cannabis is famous for. These are the two components of cannabis that have been most studied by scientists.
Cannabidiol is as versatile as THC, if not more so, and has worked its way into a host of products.
C annabidiol, or CBD for short, is a non-intoxicating cannabinoid found in cannabis. Cannabidiol is the second-most abundant cannabinoid in the plant after tetrahydrocannabinol (THC). It has many potential therapeutic benefits, including anti-inflammatory, analgesic, anti-anxiety, and seizure-suppressant properties. CBD can be sourced from both marijuana and hemp plants.
The mosaic of laws that govern CBD legality across the globe varies just as much as the legislation across the United States. Most Group of 20 (G20) countries allow CBD extracted from industrial hemp, but not CBD extracted from whole-plant marijuana.
Industrial hemp and whole-plant marijuana
CBD is the yang to THC’s yin; it may calm anxiety and elevate your level of chill without intoxication.
AC/DC : A sativa-dominant phenotype of Cannatonic, this cultivar boasts one of the highest ratios of CBD to THC, clocking in at 20:1.
Research into CBD has been conducted for the following conditions.
Consumers report using CBD for a huge variety of health and wellness reasons, but significantly more research is needed to determine the symptoms and ailments it can most successfully treat. Currently, there are over 60 clinical trials are examining the effectiveness of CBD for a variety of conditions.