Posted on

cbd oil bioavailability

But, don’t let that stand in your way. Not only do those recipes taste incredible, they also offer a subtler effect for those just starting out with CBD. Simply add a dropper or two of the CBD Oral Drops to your next bake or post-workout smoothie, and the Juniper Lime flavouring will lend a delicate citrus twist.

Here, we break down everything you need to know about CBD bioavailability, from the most absorbent methods to simple tips that enhance your experience.

The fast absorption means you should experience the effects quickly, reaping the benefits of CBD just 15-30 minutes after ingestion. Try it with our CBD Oil Drops, which are infused with a clean, bright Juniper Lime flavouring that makes sublingual application all the more enjoyable.

More Ways to Increase CBD Bioavailability

While the bioavailability of topical CBD hasn’t been quantified, it’s believed to serve a whole new purpose compared to the CBD you consume. You see, a CBD balm or cream isn’t able to enter the bloodstream, but experts believe it can interact with local cannabinoid receptors in the spot you apply it.

It’s important to keep bioavailability in mind when choosing CBD, as it can alter the effects you experience, boosting them up or dialling them down. You might think increasing the milligrams equals increasing the strength – and it can help – but bioavailability also plays a key role in delivering the CBD effects you want. So, let’s look at the options.

One easy way to enhance the bioavailability of CBD is to use a higher concentration of your go-to product. While this doesn’t make it more absorbent, it does mean more milligrams of CBD will enter your bloodstream. Just keep in mind that the FSA recommends no more than 70mg per day.

You might have heard CBD experts talking about bioavailability, but what does it actually mean? And why is it a vital factor when picking CBD products?

When CBD is inhaled, such as through a vape pen or vaporizer, it can be absorbed through your lungs nearly immediately. From there, the CBD directly enters your bloodstream, allowing it to travel and bind to the appropriate endocannabinoid receptors throughout your body. With each subsequent breath, you inhale more CBD, providing yourself with a continuous dose of CBD that can be absorbed quickly (within minutes) and efficiently (direct entry through the lungs).

Oral ingestion is popular because it’s a method people are already familiar with, from eating food, drinking beverages, and swallowing daily vitamin. Unfortunately, while oral ingestion may be common, it’s also the least effective method for taking CBD. The oral bioavailability of CBD is between 10% to 20%, although some studies have found it to be as low as 6%.

Intranasal Bioavailability of CBD

CBD has an intranasal bioavailability of 34% to 46%, although some studies have reported rates as high as 56%. Inhaling CBD is the most effective method for ensuring a high bioavailability.

The bioavailability of CBD oil largely depends on the method of administration you use to administer it—in other words, how you consume the CBD. There are many ways to take CBD, from gummies and edibles to vapes and topical products. Each of these methods has a different bioavailability.

Times are exciting in the world of CBD right now. As an emerging therapy, research is well underway, looking into its potential health benefits. Meanwhile, it seems like a new, innovative CBD product gets introduced daily, from the latest CBD cream to chewing gum.

A more elaborate and less irritating inhalation form similar to smoking is vaping — which is done with a vaporizer pen.

By contrast, the mean residence time for injected CBD, in the same study, was 3.3 hours [3].

But, in order to be effective CBD has to reach your endocannabinoid system. This means it first needs to be absorbed into your bloodstream, a concept known as bioavailability.

1. Smoking

Inhalation is an efficient way to consume CBD because it bypasses the digestive tract and liver allowing CBD to be readily absorbed through the thin membranes that line the air sacs of the lungs (alveoli) where it enters directly into the bloodstream. There are several ways to inhale CBD.

However, the low absorption of oral CBD may be offset by certain advantages — such as a longer duration. A laboratory animal study found the average amount of time an orally consumed CBD molecule stays in the body, known as the “mean residence time”, was 4.2 hours.

Not all CBD is the same. Discover the differences between CBD delivery forms and the pros and cons of each. Learn how to choose the best CBD form for you.

Oral CBD has also been found to lead to higher brain levels when compared to inhalation methods in animal studies [6].