Posted on

cannabis oil what is it used for

Other forms of cannabis are solid and are usually sold either as resin or dried plant material. In commercially-produced medical cannabis oils, the concentrations of CBD and THC tend to be well-controlled, which makes it easy to calculate doses.

Cannabis oil can only be sold legally in Britain if it contains less than 0.05% THC. But the nation’s medicines regulator, the MHRA, announced recently that even pure CBD could not be sold as a medicine without first going through the usual clinical testing and safety checks required for all new medicines. This month, the US Food and Drug Administration will consider the approval of Epidiolex, a CBD-based medicine from GW Pharmaceuticals, which has completed such clinical trials. The European Medicines Agency (EMA) will rule on the drug early next year. If the EMA approves Epidiolex, it could be available to prescribe to named patients in Britain next year, Brexit notwithstanding.

Does it work as a medicine?

Four drugs based on cannabis compounds are already on the market in Europe. Among them are Nabilone, a synthetic compound that mimics THC, is prescribed for nausea and vomiting caused by chemotherapy, and Sativex, an oil that contains equal parts THC and CBD, is used to treat muscle spasms in multiple sclerosis. Both contain too much THC to administer to children. “The only medicines that are approved in the UK would get children stoned,” said David Nutt, professor of neuropsychopharmacology at Imperial College, London.

Cannabis oils are extracts from cannabis plants. Unprocessed, they contain the same 100 or so active ingredients as the plants, but the balance of compounds depends on the specific plants the oil comes from. The two main active substances in cannabis plants are cannabidiol, or CBD, and delta-9 tetrahydrocannabinol, or THC. Oil extracted from hemp plants can contain a lot of CBD, while oil from skunk plants will contain far more THC. THC produces the high that recreational cannabis users seek, while oils for medical use contain mostly CBD.

CBD is an anticonvulsant, and some other compounds in the plant, including THC and cannabidivarin, may be too. There is good evidence from clinical trials in the US and Europe that pharmaceutical preparations of CBD can treat two severe forms of childhood epilepsy known as Dravet syndrome and Lennox-Gastaut syndrome. Both forms of epilepsy often fail to improve with existing epilepsy drugs. CBD is generally considered safe, but some trials have reported side effects including dry mouth, lightheadedness and altered liver enzyme activity.

Although there is some scientific evidence that THC has potential to control convulsions, its mind-altering effects mean that much of the focus has turned to cannabidiol – particularly for childhood epilepsies that conventional drugs fail to control.

The situation is less clear when it comes to the use of commercial cannabis oils to control seizures, where the evidence is mainly anecdotal, and the oils can contain differing concentrations of cannabidiol and THC.

Advertisement

That’s a complicated question. In the UK cannabidiol is legal. Cannabis plant extracts (known as hemp or CBD oils) are available in high-street stores but the THC content must be below 0.2 per cent. “THC is not psychoactive at this level,” says David Nutt, a neuropsychopharmacologist at Imperial College London. But cannabidiol is illegal in many other countries.

What is cannabis oil?

So can cannabis oil make you high?

CBD oil contains CBD mixed with an inert carrier oil, such as coconut oil or hemp seed oil. The bottled oil, called a tincture, is sold in various concentrations. There are also CBD capsules, CBD gummies, and under-the-tongue CBD sprays.

There are no guidelines for the appropriate use of CBD oil. CBD oil is usually delivered sublingually (under the tongue). Most oils are sold in 30-milliliter (mL) bottles with a dropper cap.

This cannabis extract may help treat nerve pain, anxiety, and epilepsy

Proponents claim that CBD oil can treat a wide variety of health problems, including:

CBD oil may also increase liver enzymes (a marker of liver inflammation). People with liver disease should use CBD oil with caution, ideally under the care of a doctor who can regularly check blood liver enzyme levels.

To use CBD oil, place one or more drops under the tongue and hold the dose there for 30 to 60 seconds without swallowing. Capsules and gummies are easier to dose, although they tend to be more costly. CBD sublingual sprays are available as well.