Here are a few tips to help you find the best CBD oil:
CBD oil contains CBD mixed with an inert carrier oil, such as coconut oil or hemp seed oil. The bottled oil, called a tincture, is sold in various concentrations. There are also CBD capsules, CBD gummies, and under-the-tongue CBD sprays.
If you are thinking about using CBD oil to treat a health condition, be sure to speak with your healthcare provider to ensure that it is the right option for you.
What to Look For
As CBD grows in popularity, so does the research on it but there are currently few clinical studies on the effects of CBD oil. As such, some of these claims are better supported by studies than others.
Clinical research has shown that CBD oil can trigger side effects. Severity and type can vary from one person to the next.
Medical marijuana is frequently prescribed to people with intractable (treatment-resistant) pain, including those with terminal cancer. There is some evidence that CBD contributes to this benefit.
To determine an exact dose of CBD, remember that each drop of oil equals 0.05 mL of fluid. This means that a 30-mL bottle of CBD oil will have roughly 600 drops. If the concentration of the tincture is 1,500 mg/mL, one drop would contain 2.5 mg of CBD (1,500 mg ÷ 600 drops = 2.5 mg).
However, it’s important to remember that research is still in its infancy and experts do not yet fully understand the potential long-term impacts of CBD usage. For that reason, you should always discuss your CBD use with your doctor.
Some dosages that have been used in research studies for different conditions include:
Unless your doctor recommends a specific dose, start by taking 10 to 20 mg a day. Take this for a week to ensure that it is well-tolerated and that you don’t experience any unwanted effects or an allergic reaction.
How to Take CBD
If you are targeting specific symptoms of a condition, taking an oil, capsule, or gummy might be a better way to obtain a higher, more concentrated dose.
The dosages used in research studies vary and there is no consensus on how much should be used for specific conditions. If you do decide to try CBD, it is also important to note that there is no universally agreed upon dose. Research also suggests that people may respond differently to various dosages, so the amount that is right for your needs might vary.
One 2020 review of studies found that participants showed improvements in anxiety levels after single doses of CBD ranging from 300 to 600 mg. Such results indicate that the CBD may hold promise as a treatment to alleviate symptoms of acute anxiety.
Topical applications may produce localized effects, but they are unlike to have any mental health benefits.
For someone with a bodyweight of 70kg, and where the product is standardised to 17% CBD, the optimal dose would be 25mg, although this can be gradually increased to 50mg depending on the results obtained (though this higher dose should not be exceeded). CBD can also be vaporised but the most stable and consistent mode of administration is expertly-dosed, oral capsules.
What are the effects of CBD 25mg?
This depends on several factors:
What’s the right CBD dose for optimal efficacy?
Once ingested, CBD is rapidly distributed around the body. It is lipophilic and thus quickly crosses the blood-brain barrier to reach brain tissues. It has no effect on heart rate, blood pressure or body temperature. CBD’s half-life is around 9 hours after which it is excreted in a metabolised form in urine.
Unlike THC, which has a strong affinity for CB1 receptors, CBD binds more to CB2 receptors. These are found on the surface of cells of the central nervous system and in particular in immune system tissues where they are involved in modulating memory, emotions and pain (chronic, inflammatory or neuropathic) (2-3).
It is a natural compound which mimics the action of endocannabinoid messengers produced by the body. Like them, it is able to bind to specific receptors (CB1 and CB2) located on external cell membranes, and trigger various cellular responses such as restricting synaptic transmission, relieving pain and reducing spontaneous locomotion (1). Just like endogenous cannabinoids, CBD thus inhibits the transmission of small-diameter nociceptive fibres (which are involved in the pain process) and reduces the release of neurotransmitters like substance P, responsible for transmitting pain.
Unlike the drug cannabis which usually contains around 15% THC, the form used in this product has none. It therefore has no psychotropic effects and has an excellent safety profile in humans.